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MANNITOL BP2007/USP34 CAS:87-78-5

Model No.: nc23
Product Name: MANNITOL BP2007/USP34 CAS:87-78-5
Product Origin: Zhengzhou,China
Standard: BP2007/USP34
Brand Name: NC
PriceTerms: T/T,DP,L/C
Supply Ability: 100MT/MONTH
Detailed Product Description:

Mannitol has six alcohol is due to endothermic dissolution, sweet, have oral discomfort, it is more widely used in medicine to sober up, mouth refreshing agent chewable tablets manufacturing. Mannitol used for the food industry, chemical industry, pharmaceutical industry.


E No:E421

CAS No:585-55-6

Einecs No:200-711-8

HS Code:29054300

Specification:BP/USP/EP/CP/FCC IV

Routine Packing:25kg

Place of origin:China


Payment terms:T/T or L/C

Port of dispapch:anghai,Qindao

Applications:Mannitol for maltose in the food, chewing gum, cakes, bodybuilding foods. Mannitol in the industry for the plastics industry, the system rosin esters, synthetic glycerol resins, explosives, detonators, etc.


Specification-- BP/USP/EP/CP/FCC IV


Mannitol; Manitol; Mannite


white crystalline powder




conformed to the standard



Molecular Formula


Melting point


Solution clarification


Specific Optical Rotation






Reducing Sugars


Related Substances:

The area of any peak


Total Impurities








Loss on drying


Residue on ignition


Heavy metals





Bacterial Endotoxins


Microbial Contamination:

Escherichia Coli


Mannitol nature:
White needle crystal. Melting point 166, the relative density of 1.52,1.489 (20 ℃), boiling point 290-295 ℃ (467kPa). 1g Mannitol E421 can be dissolved in about 5.5ml of water (about 18%, 25 ℃), 83ml alcohol, more soluble in water, soluble in pyridine and aniline, insoluble in ether. Aqueous solution is alkaline. E421 is sorbitol isomerization body, sorbitol hygroscopicity strong, and the product no moisture absorption. E421 sweet, its sweetness equivalent to sucrose 70%.

Mannitol uses:
The pleasant taste and mouthfeel of E421 also makes E421 a popular excipient for chewable tablets.
Mannitol in medicine is a good diuretic to reduce intracranial pressure, intraocular pressure and renal drugs, dehydration, sugar substitutes, also used as tablet excipients and solid, liquid diluent. E421 injection as the high penetration of antihypertensive drugs, the clinical brain disorders, especially rescue the rescue of a drug commonly used, Mannitol to reduce intracranial pressure with antihypertensive drugs require rapid, effective and accurate. Mannitol used as a tablet excipients, Mannitol no moisture absorption, fast drying, good chemical stability, but also has tasty, and good grain characteristics, Mannitol for anti-cancer drugs, antibiotics, antihistamines and vitamins, and most other tablets. In addition, Mannitol is also used to sober up drugs, mouth refreshing agent Chewable agent. In the food sector, Mannitol in sugar and sugar alcohols in the minimum water absorption, and sweet with a refreshing, for maltose, chewing gum, cakes and other foods of anti-sticking, and as a general anti-sticking pastry flour. Mannitol can also be used in patients with diabetes, food, fitness and food low calorific value, low-sugar sweetener.
In industry, Mannitol can be used for the plastics industry, manufacturing rosin ester resins and synthetic glycerin, explosives, detonators (nitrification mannitol) and so on. In the chemical analysis for the determination of boron in biological testing for bacterial culture on the agent. Mannitol, although that can be absorbed by the gastrointestinal, but does not accumulate in the body. Mannitol is absorbed, is metabolized in the body part, other part in the urine; by hydrobromic acid can be obtained dibromo mannitol.
Currently, the worlds industrial production Mannitol has two main kinds of processes, one based on kelp as raw materials in the production of alginate at the same time, will be submitted after kelp iodine soaking, after repeated Concentration, impurity, from the cross, evaporation, cooling crystallization derived from Mannitol; One is based on sucrose and glucose as raw material by hydrolysis, epimerization and isomerization enzyme, and then hydrogenation Mannitol.

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