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D-Mannitol

Model No.: CAS:87-78-5
Product Name: D-Mannitol
Product Origin: China
Standard: BP2007/USP34
Brand Name: NC
PriceTerms: USD
Supply Ability: Enough stock
Detailed Product Description:

Mannitol has six alcohol is due to endothermic dissolution, sweet, have oral discomfort, it is more widely used in medicine to sober up, mouth refreshing agent chewable tablets manufacturing. Mannitol used for the food industry, chemical industry, pharmaceutical industry.

Mannitol

E No:E421

CAS No:585-55-6

Einecs No:200-711-8

HS Code:29054300

Specification:BP/USP/EP/CP/FCC IV

Routine Packing:25kg

Place of origin:China

QC:ISO

Payment terms:T/T or L/C

Port of dispapch:anghai,Qindao

Applications:Mannitol for maltose in the food, chewing gum, cakes, bodybuilding foods. Mannitol in the industry for the plastics industry, the system rosin esters, synthetic glycerol resins, explosives, detonators, etc.

Item

Specification-- BP/USP/EP/CP/FCC IV

Name

Mannitol; Manitol; Mannite

Appearance

white crystalline powder

Acidity

≤0.30ml
≤0.13ml

Identification

conformed to the standard

Assay

98.0-102.0%

Molecular Formula

C6H14O6

Melting point

166-170℃

Solution clarification

conform

Specific Optical Rotation

+23o~+25o

TLC

Conformity

Conductivity

≤20us/cm

Reducing Sugars

≥12.8ml

Related Substances:

The area of any peak

≤2%

Total Impurities

≤2%

Chloride

≤0.003%

Sulphate

≤0.01%

Oxalate

≤0.02%

Loss on drying

≤0.5%

Residue on ignition

≤0.1%

Heavy metals

≤10ppm

As

≤2ppm

Microbiology

Bacterial Endotoxins

≤2.5IU/g

Microbial Contamination:

TAMC
TYMC
Escherichia Coli
Salmonella

≤100cfu/g
≤100cfu/g
Negative
Negative

Mannitol nature:
White needle crystal. Melting point 166, the relative density of 1.52,1.489 (20 ℃), boiling point 290-295 ℃ (467kPa). 1g Mannitol E421 can be dissolved in about 5.5ml of water (about 18%, 25 ℃), 83ml alcohol, more soluble in water, soluble in pyridine and aniline, insoluble in ether. Aqueous solution is alkaline. E421 is sorbitol isomerization body, sorbitol hygroscopicity strong, and the product no moisture absorption. E421 sweet, its sweetness equivalent to sucrose 70%.

Mannitol uses:
The pleasant taste and mouthfeel of E421 also makes E421 a popular excipient for chewable tablets.
Mannitol in medicine is a good diuretic to reduce intracranial pressure, intraocular pressure and renal drugs, dehydration, sugar substitutes, also used as tablet excipients and solid, liquid diluent. E421 injection as the high penetration of antihypertensive drugs, the clinical brain disorders, especially rescue the rescue of a drug commonly used, Mannitol to reduce intracranial pressure with antihypertensive drugs require rapid, effective and accurate. Mannitol used as a tablet excipients, Mannitol no moisture absorption, fast drying, good chemical stability, but also has tasty, and good grain characteristics, Mannitol for anti-cancer drugs, antibiotics, antihistamines and vitamins, and most other tablets. In addition, Mannitol is also used to sober up drugs, mouth refreshing agent Chewable agent. In the food sector, Mannitol in sugar and sugar alcohols in the minimum water absorption, and sweet with a refreshing, for maltose, chewing gum, cakes and other foods of anti-sticking, and as a general anti-sticking pastry flour. Mannitol can also be used in patients with diabetes, food, fitness and food low calorific value, low-sugar sweetener.
In industry, Mannitol can be used for the plastics industry, manufacturing rosin ester resins and synthetic glycerin, explosives, detonators (nitrification mannitol) and so on. In the chemical analysis for the determination of boron in biological testing for bacterial culture on the agent. Mannitol, although that can be absorbed by the gastrointestinal, but does not accumulate in the body. Mannitol is absorbed, is metabolized in the body part, other part in the urine; by hydrobromic acid can be obtained dibromo mannitol.
Currently, the worlds industrial production Mannitol has two main kinds of processes, one based on kelp as raw materials in the production of alginate at the same time, will be submitted after kelp iodine soaking, after repeated Concentration, impurity, from the cross, evaporation, cooling crystallization derived from Mannitol; One is based on sucrose and glucose as raw material by hydrolysis, epimerization and isomerization enzyme, and then hydrogenation Mannitol.

MANNITOL BP2007/USP34 CAS:87-78-5

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